@article {420,
	title = {In vivo NMR and MRI using injection delivery of laser-polarized xenon},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {94},
	year = {1997},
	note = {P Natl Acad Sci USAYn574Times Cited:55Cited References Count:39},
	month = {Dec 23},
	pages = {14725-14729},
	abstract = {<p>Because xenon NMR is highly sensitive to the local environment, laser-polarized xenon could be a unique probe of living tissues. Realization of clinical and medical science applications beyond lung airspace imaging requires methods of efficient delivery of laser-polarized xenon to tissues, because of the short spin-lattice relaxation times and relatively low concentrations of xenon attainable in the body. Preliminary results from the application of a polarized xenon injection technique for in vivo Xe-129 NMR/MRI are extrapolated along with a simple model of xenon transit to show that the peak local concentration of polarized xenon delivered to tissues by injection may exceed that delivered by respiration by severalfold.</p>
},
	keywords = {humans},
	isbn = {0027-8424},
	doi = {Doi 10.1073/Pnas.94.26.14725},
	url = {<Go to ISI>://WOS:000071182800090},
	author = {Goodson, B. M. and Song, Y. Q. and Taylor, R. E. and Schepkin, V. D. and Brennan, K. M. and Chingas, G. C. and Budinger, T. F. and Navon, G. and Pines, A.}
}
