@article {3083, title = {Realization of portable room temperature nanodiamond 13C hyperpolarizer}, year = {Submitted}, author = {A. Ajoy and R. Nazaryan and E. Druga and K. Liu and B. Han and J.T. Oon and M. Gierth and R. Tsang and J.H. Walton and C.A. Meriles and J.A. Reimer and D. Suter and A. Pines} } @article {3170, title = {Dynamics of frequency-swept nuclear spin optical pumping in powdered diamond at low magnetic fields}, journal = {Proceedings of the National Academy of Science}, year = {2019}, month = {01/2019}, abstract = {

A broad effort is underway to improve the sensitivity of NMR through the use of dynamic nuclear polarization. Nitrogen vacancy (NV) centers in diamond offer an appealing platform because these paramagnetic defects can be optically polarized efficiently at room temperature. However, work thus far has been mainly limited to single crystals, because most polarization transfer protocols are sensitive to misalignment between the NV and magnetic field axes. Here we study the spin dynamics of NV\−13C pairs in the simultaneous presence of optical excitation and microwave frequency sweeps at low magnetic fields. We show that a subtle interplay between illumination intensity, frequency sweep rate, and hyperfine coupling strength leads to efficient, sweep-direction-dependent 13C spin polarization over a broad range of orientations of the magnetic field. In particular, our results strongly suggest that finely tuned, moderately coupled nuclear spins are key to the hyperpolarization process, which makes this mechanism distinct from other known dynamic polarization channels. These findings pave the route to applications where powders are intrinsically advantageous, including the hyperpolarization of target fluids in contact with the diamond surface or the use of hyperpolarized particles as contrast agents for in vivo imaging.

}, issn = {0027-8424}, doi = { https://doi.org/10.1073/pnas.1811994116 }, url = {https://www.pnas.org/content/early/2019/01/23/1811994116}, author = {P.R. Zangara and S. Dhomkar and A. Ajoy and K. Liu and R. Nazaryan and D. Pagliero and D. Suter and J. Reimer and A. Pines and C. Meriles} } @article {2981, title = {Wide dynamic range magnetic field cycler: Harnessing quantum control at low and high fields}, journal = {Review of Scientific Instruments }, volume = {90}, year = {2019}, month = {01/2019}, abstract = {

We describe the construction of a fast field cycling device capable of sweeping a 4-order-of-magnitude range of magnetic fields, from \∼1 mT to 7 T, in under 700 ms, and which is further extendable to a 1 nT-7 T range. Central to this system is a high-speed sample shuttling mechanism between a superconducting magnet and a magnetic shield, with the capability to access arbitrary fields in between with high resolution. Our instrument serves as a versatile platform to harness the inherent dichotomy of spin dynamics on offer at low and high fields\—in particular, the low anisotropy, fast spin manipulation, and rapid entanglement growth at low field as well as the long spin lifetimes, spin specific control, and efficient inductive measurement possible at high fields. Exploiting these complementary capabilities in a single device opens up applications in a host of problems in quantum control, sensing, and information storage, besides in nuclear hyperpolarization, relaxometry, and imaging. In particular, in this paper, we focus on the ability of the device to enable low-field hyperpolarization of 13C nuclei in diamond via optically pumped electronic spins associated with nitrogen vacancy defect centers.

}, doi = {https://doi.org/10.1063/1.5064685}, url = {https://aip.scitation.org/doi/10.1063/1.5064685}, author = {A. Ajoy and X. Lv and E. Druga and K. Liu and B. Safvati and A. Morabe and M. Fenton and R. Nazaryan and S. Patel and T. Sjolander and J. Reimer and D Sakellariou and C. Meriles and A. Pines} } @article {2980, title = {Enhanced dynamic nuclear polarization via swept microwave frequency combs}, journal = {Proc. Natl. Acad. Sci}, year = {2018}, month = {10/2018}, abstract = {

Dynamic nuclear polarization (DNP) has enabled enormous gains in magnetic resonance signals and led to vastly accelerated NMR/MRI imaging and spectroscopy. Unlike conventional cw-techniques, DNP methods that exploit the full electron spectrum are appealing since they allow direct participation of all electrons in the hyperpolarization process. Such methods typically entail sweeps of microwave radiation over the broad electron linewidth to excite DNP but are often inefficient because the sweeps, constrained by adiabaticity requirements, are slow. In this paper, we develop a technique to overcome the DNP bottlenecks set by the slow sweeps, using a swept microwave frequency comb that increases the effective number of polarization transfer events while respecting adiabaticity constraints. This allows a multiplicative gain in DNP enhancement, scaling with the number of comb frequencies and limited only by the hyperfine-mediated electron linewidth. We demonstrate the technique for the optical hyperpolarization of 13C nuclei in powdered microdiamonds at low fields, increasing the DNP enhancement from 30 to 100 measured with respect to the thermal signal at 7T. For low concentrations of broad linewidth electron radicals [e.g., TEMPO ((2,2,6,6-tetramethylpiperidin-1-yl)oxyl)], these multiplicative gains could exceed an order of magnitude.

}, doi = {1807125115}, url = {https://doi.org/10.1073/pnas.1807125115}, author = {Ashok Ajoy and Kristina Liu and Xudong Lv and Raffi Nazaryan and G.Wang and E . Druga and Jeff Reimer and Ditter Suter and C. Ramanathan and C.A Meriles and Alexander Pines} } @article {2979, title = {Orientation independent room-temperature optical 13C hyperpolarization in powdered diamond}, journal = {Science Advances}, volume = {4}, year = {2018}, month = {05/2018}, abstract = {

Dynamic nuclear polarization via contact with electronic spins has emerged as an attractive route to enhance the sensitivity of nuclear magnetic resonance beyond the traditional limits imposed by magnetic field strength and temperature. Among the various alternative implementations, the use of nitrogen vacancy (NV) centers in diamond\—a paramagnetic point defect whose spin can be optically polarized at room temperature\—has attracted widespread attention, but applications have been hampered by the need to align the NV axis with the external magnetic field. We overcome this hurdle through the combined use of continuous optical illumination and a microwave sweep over a broad frequency range. As a proof of principle, we demonstrate our approach using powdered diamond with which we attain bulk 13C spin polarization in excess of 0.25\% under ambient conditions. Remarkably, our technique acts efficiently on diamond crystals of all orientations and polarizes nuclear spins with a sign that depends exclusively on the direction of the microwave sweep. Our work paves the way toward the use of hyperpolarized diamond particles as imaging contrast agents for biosensing and, ultimately, for the hyperpolarization
of nuclear spins in arbitrary liquids brought in contact with their surface.

}, doi = {10.1126/sciadv.aar5492 }, url = {http://advances.sciencemag.org/content/4/5/eaar5492}, author = {Ashok Ajoy and Kristina Liu and Raff Nazaryan and Xudong Lv and Pablo R. Zangara and Benjamin Safvati and Guoqing Wang and Daniel Arnold and Grace Li and Arthur Lin and Priyanka Raghavan and Emanuel Druga and Siddharth Dhomkar and Daniela Pagliero and Jeffrey A. Reimer and Dieter Suter and Carlos A. Meriles and Alexander Pines} } @article {2391, title = {An optimized microfabricated platform for the optical generation and detection of hyperpolarized 129Xe}, journal = {Scientific Reports }, year = {2017}, url = {http://www.nature.com/articles/srep43994}, author = {Daniel J. Kennedy and Scott J. Seltzer and Ricardo Jimenez-Martinez and Hattie L. Ring and Nicholas Malecek and Svenja Knappe and Elizabeth Donley and John Kitching and Vikram S. Bajaj and Alexander Pines} } @article {1867, title = {129Xe NMR Relaxation-Based Macromolecular Sensing}, journal = {JACS Communication}, volume = {138}, year = {2016}, month = {07/2016}, chapter = {9747}, author = {Muller Gomes and Phuong Dao and Keunghong Jeong and Clancy Slack and Christophoros Vassiliou and Matthew B. Francis and David Wemmer and Alexander Pines} } @article {1866, title = {Investigation of DOTA-Metal Chelation Effects on 129Xe Chemical Shift}, journal = {ChemPhysChem}, year = {2015}, author = {Keunhong Jeong and Clancy C. Slack and Christophoros C. Vassiliou and Phuong Dao and Muller D Gomes and Daniel J. Kennedy and Ashley E. Truxal and Lindsay J Sperling and Matthew B. Francis and David E. Wemmer and Alexander Pines} } @article {1478, title = {Optical hyperpolarization and NMR detection of 129Xe on a microfluidic chip}, journal = {Nature Communication}, volume = {5}, year = {2014}, pages = {3908}, doi = {10.1038/ncomms4908}, author = {Jimenez-Martinez, R. and Kennedy, D. J. and Rosenbluh, M. and Donley, E. A. and Knappe, S. and Seltzer, S. J. and Ring, H. and Bajaj, V.S. and Kitching, J.} } @article {260, title = {Investigation of antirelaxation coatings for alkali-metal vapor cells using surface science techniques}, journal = {Journal of Chemical Physics}, volume = {133}, year = {2010}, note = {J. Chem. Phys.ISI Document Delivery No.: 667NNTimes Cited: 6Cited Reference Count: 81Seltzer, S. J. Michalak, D. J. Donaldson, M. H. Balabas, M. V. Barber, S. K. Bernasek, S. L. Bouchiat, M. -A. Hexemer, A. Hibberd, A. M. Kimball, D. F. Jackson Jaye, C. Karaulanov, T. Narducci, F. A. Rangwala, S. A. Robinson, H. G. Shmakov, A. K. Voronov, D. L. Yashchuk, V. V. Pines, A. Budker, D.Office of Science, Office of Basic Energy Sciences, Materials Sciences Division and Nuclear Science Division, of the U. S. Department of Energy [DE-AC02-05CH11231]; NSF/DST [PHY-0425916]; Office of Naval Research (ONR) [N0001409WX21049]The authors thank Daniel Fischer, Kristin Schmidt, and Ed Kramer for assistance with the NEXAFS measurements, and Joel Ager, Joshua Wnuk, David Trease, and Gwendal Kervern for helpful discussions and other assistance. S.J.S., D.J.M., M. H. D., A. P., and D. B., the Advanced Light Source, and the DSC, FTIR, and AFM studies were supported by the Director, Office of Science, Office of Basic Energy Sciences, Materials Sciences Division and Nuclear Science Division, of the U. S. Department of Energy under Contract No. DE-AC02-05CH11231 at Lawrence Berkeley National Laboratory. Other parts of this work were funded by the NSF/DST under Grant No. PHY-0425916 for U.S.-India cooperative research, by an Office of Naval Research (ONR) MURI grant, and by ONR under Grant No. N0001409WX21049.AMER INST PHYSICSMELVILLE}, month = {October 11, 2010}, pages = {144703}, type = {Article}, chapter = {144703}, abstract = {

Many technologies based on cells containing alkali-metal atomic vapor benefit from the use of antirelaxation surface coatings in order to preserve atomic spin polarization. In particular, paraffin has been used for this purpose for several decades and has been demonstrated to allow an atom to experience up to 10 000 collisions with the walls of its container without depolarizing, but the details of its operation remain poorly understood. We apply modern surface and bulk techniques to the study of paraffin coatings in order to characterize the properties that enable the effective preservation of alkali spin polarization. These methods include Fourier transform infrared spectroscopy, differential scanning calorimetry, atomic force microscopy, near-edge x-ray absorption fine structure spectroscopy, and x-ray photoelectron spectroscopy. We also compare the light-induced atomic desorption yields of several different paraffin materials. Experimental results include the determination that crystallinity of the coating material is unnecessary, and the detection of CvC double bonds present within a particular class of effective paraffin coatings. Further study should lead to the development of more robust paraffin antirelaxation coatings, as well as the design and synthesis of new classes of coating materials. (C) 2010 American Institute of Physics. [doi:10.1063/1.3489922]

}, keywords = {SPECTROSCOPY}, isbn = {0021-9606}, doi = {10.1063/1.3489922}, url = {http://link.aip.org/link/doi/10.1063/1.3489922}, author = {Seltzer, S. J. and Michalak, D. J. and Donaldson, M. H. and Balabas, M. V. and Barber, S. K. and Bernasek, S. L. and Bouchiat, M. A. and Hexemer, A. and Hibberd, A. M. and Kimball, D. F. J. and Jaye, C. and Karaulanov, T. and Narducci, F. A. and Rangwala, S. A. and Robinson, H. G. and Shmakov, A. K. and Voronov, D. L. and Yashchuk, V. V. and Pines, A. and Budker, D.} } @article {264, title = {Xenon-based molecular sensors in lipid suspensions}, journal = {Journal of Magnetic Resonance}, volume = {205}, year = {2010}, note = {J Magn Reson627SZTimes Cited:8Cited References Count:23}, month = {Aug}, pages = {242-246}, abstract = {

There have been many proposals to use xenon-based molecular sensors in biological settings. Fundamental to understanding the properties of these sensors in vivo is characterizing their behavior in lipid environments. We report the investigation of xenon-based molecular sensors in suspensions of lipid vesicles with a size comparable to cells. We detail spectroscopic properties of sensors associated with lipid vesicles as well as those in equilibrium in the surrounding solution. We characterize the dependence of the spectral parameters on temperature, relevant for studies at physiological temperatures. We also demonstrate the ability to perform selective saturation transfer (Hyper-CEST) between sensor, both lipid bound and unbound, and the bulk solution. Lastly, we demonstrate the applicability of saturation transfer in the heterogeneous medium as an imaging modality. (C) 2010 Elsevier Inc. All rights reserved.

}, keywords = {binding}, isbn = {1090-7807}, doi = {Doi 10.1016/J.Jmr.2010.05.005}, url = {://WOS:000280064500008}, author = {Meldrum, T. and Schroder, L. and Denger, P. and Wemmer, D. E. and Pines, A.} } @article {269, title = {Distortion-free magnetic resonance imaging in the zero-field limit}, journal = {Journal of Magnetic Resonance}, volume = {200}, year = {2009}, note = {J Magn Reson526AWTimes Cited:6Cited References Count:29}, month = {Oct}, pages = {285-290}, abstract = {

MRI is a powerful technique for clinical diagnosis and materials characterization. Images are acquired in a homogeneous static magnetic field much higher than the fields generated across the field of view by the spatially encoding field gradients. Without such a high field, the concomitant components of the field gradient dictated by Maxwell\&$\#$39;s equations lead to severe distortions that make imaging impossible with conventional MRI encoding. In this paper, we present a distortion-free image of a phantom acquired with a fundamentally different methodology in which the applied static field approaches zero. Our technique involves encoding with pulses of uniform and gradient field, and acquiring the magnetic field signals with a SQUID. The method can be extended to weak ambient fields, potentially enabling imaging in the Earth\&$\#$39;s field without cancellation coils or shielding. Other potential applications include quantum information processing and fundamental studies of long-range ferromagnetic interactions. (C) 2009 Elsevier Inc. All rights reserved.

}, keywords = {gradients}, isbn = {1090-7807}, doi = {Doi 10.1016/J.Jmr.2009.07.016}, url = {://WOS:000272260900015}, author = {Kelso, N. and Lee, S. K. and Bouchard, L. S. and Demas, V. and M{\"u}ck, M. and Pines, A. and Clarke, J.} } @article {271, title = {{\textquoteright}Ex situ{\textquoteright} magnetic resonance volume imaging}, journal = {Chemical Physics Letters}, volume = {467}, year = {2009}, note = {Chem Phys Lett386VCTimes Cited:2Cited References Count:25}, month = {Jan 5}, pages = {398-401}, abstract = {

The portable NMR community has introduced advances that have allowed for a variety of studies. Imaging of static and moving objects has almost become standardized. The inherent static field gradients of portable systems have, however, limited such studies to imaging of slices perpendicular to the main gradient; full volume imaging in transportable, open systems has not been actively pursued. We present a true three-dimensional image of a phantom in an ex situ, electromagnet-based system. The basic concepts and designs put forth here extend in a straightforward fashion to higher fields and imaging of larger samples by ex situ methodologies. (C) 2008 Elsevier B.V. All rights reserved.

}, keywords = {array}, isbn = {0009-2614}, doi = {Doi 10.1016/J.Cplett.2008.11.069}, url = {://WOS:000261909700037}, author = {Demas, V. and Franck, J. M. and Bouchard, L. S. and Sakellariou, D. and Meriles, C. A. and Martin, R. and Prado, P. J. and Bussandri, A. and Reimer, J. A. and Pines, A.} } @article {270, title = {Shimmed matching pulses: Simultaneous control of rf and static gradients for inhomogeneity correction}, journal = {Journal of Chemical Physics}, volume = {131}, year = {2009}, note = {J Chem Phys536HUTimes Cited:4Cited References Count:30}, month = {Dec 21}, abstract = {

Portable NMR systems generally suffer from poor field homogeneity and are therefore used more commonly for imaging and relaxation measurements rather than for spectroscopy. In recent years, various approaches have been proposed to increase the sample volume that is usable for spectroscopy. These include approaches based on manual shimming and those based on clever combinations of modulated radio frequency and gradient fields. However, this volume remains small and, therefore, of limited utility. We present improved pulses designed to correct for inhomogeneous dispersion across wide ranges of frequency offsets without eliminating chemical shift or spatial encoding. This method, based on the adiabatic double passage, combines the relatively larger corrections available from spatially matched rf gradients [C. Meriles , J. Magn. Reson. 164, 177 (2003)]. with the adjustable corrections available from time-modulated static field gradients [D. Topgaard , Proc. Natl. Acad. Sci. U.S.A. 101, 17576 (2004)]. We explain the origins of these corrections with a theoretical model that simplifies and expedites the design of the pulse waveforms. We also present a generalized method for evaluating and comparing pulses designed for inhomogeneity correction. Experiments validate this method and support simulations that offer new possibilities for significantly enhanced performance in portable environments.

}, keywords = {design}, isbn = {0021-9606}, doi = {Doi 10.1063/1.3243850}, url = {://WOS:000273036300030}, author = {Franck, J. M. and Demas, V. and Martin, R. W. and Bouchard, L. S. and Pines, A.} } @article {293, title = {Application of atomic magnetometry in magnetic particle detection}, journal = {Applied Physics Letters}, volume = {89}, year = {2006}, note = {Appl Phys Lett112PJTimes Cited:9Cited References Count:18}, month = {Nov 27}, abstract = {

The authors demonstrate the detection of magnetic particles carried by water in a continuous flow using an atomic magnetic gradiometer. Studies on three types of magnetic particles are presented: a single cobalt particle (diameter similar to 150 mu m, multidomain), a suspension of superparamagnetic magnetite particles (diameter similar to 1 mu m), and ferromagnetic cobalt nanoparticles (diameter similar to 10 nm). Estimated detection limits are 20 mu m diameter for a single cobalt particle at a water flow rate of 30 ml/min, 5x10(3) magnetite particles at 160 ml/min, and 50 pl for the ferromagnetic fluid of cobalt nanoparticles at 130 ml/min. Possible applications of their method are discussed.

}, keywords = {system}, isbn = {0003-6951}, doi = {Doi 10.1063/1.2400077}, url = {://WOS:000242538500151}, author = {Xu, S. and Donaldson, M. H. and Pines, A. and Rochester, S. M. and Budker, D. and Yashchuk, V. V.} } @article {292, title = {Magnetic resonance imaging with an optical atomic magnetometer}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {103}, year = {2006}, note = {P Natl Acad Sci USA077NITimes Cited:58Cited References Count:18}, month = {Aug 22}, pages = {12668-12671}, abstract = {

We report an approach for the detection of magnetic resonance imaging without superconducting magnets and cryogenics: optical atomic magnetometry. This technique possesses a high sensitivity independent of the strength of the static magnetic field, extending the applicability of magnetic resonance imaging to low magnetic fields and eliminating imaging artifacts associated with high fields. By coupling with a remote-detection scheme, thereby improving the filling factor of the sample, we obtained time-resolved flow images of water with a temporal resolution of 0.1 s and spatial resolutions of 1.6 mm perpendicular to the flow and 4.5 mm along the flow. Potentially inexpensive, compact, and mobile, our technique provides a viable alternative for MRI detection with substantially enhanced sensitivity and time resolution for various situations where traditional MRI is not optimal.

}, keywords = {gas}, isbn = {0027-8424}, doi = {Doi 10.1073/Pnas.0605396103}, url = {://WOS:000240035900006}, author = {Xu, S. J. and Yashchuk, V. V. and Donaldson, M. H. and Rochester, S. M. and Budker, D. and Pines, A.} } @article {299, title = {Optimization of xenon biosensors for detection of protein interactions}, journal = {Chembiochem}, volume = {7}, year = {2006}, note = {Chembiochem003SDTimes Cited:39Cited References Count:25}, month = {Jan}, pages = {65-73}, abstract = {

Hyperpolarized Xe-129 NMR spectroscopy can detect the presence of specific low-concentration biomolecular analytes by means of a xenon biosensor that consists of a water-soluble, targeted cryptophane-A cage that encapsulates the xenon. In this work, we use the prototypical biotinylated xenon biosensor to determine the relationship between the molecular composition of the xenon biosensor and the characteristics of protein-bound resonances. The effects of diastereomer overlap, dipole-dipole coupling, chemical-shift anisotropy, xenon exchange, and biosensor conformotional exchange on the protein-bound biosensor signal were assessed. It was found that an optimal protein-bound biosensor signal can be obtained by minimizing the number of biosensor diastereomers and using a flexible linker of appropriate length. Both the line width and sensitivity of chemical shift to protein binding of the xenon biosensor were found to be inversely proportional to linker length.

}, keywords = {complexes}, isbn = {1439-4227}, doi = {Doi 10.1002/Cbic.200500327}, url = {://WOS:000234701000012}, author = {Lowery, T. J. and Garcia, S. and Chavez, L. and Ruiz, E. J. and Wu, T. and Brotin, T. and Dutasta, J. P. and King, D. S. and Schultz, P. G. and Pines, A. and Wemmer, D. E.} } @article {300, title = {Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L)}, journal = {Solid State Nuclear Magnetic Resonance}, volume = {29}, year = {2006}, note = {Solid State Nucl Mag999VATimes Cited:22Cited References Count:34}, month = {Feb}, pages = {183-190}, abstract = {

The peptide fragment 89-143 of the prion protein (carrying a P101L mutation) is biologically active in transgenic mice when in a fibrillar form. Injection of these fibrils into transgenic mice (expressing full length PrP with the P101L mutation) induces a neurodegenerative prion disease (Kaneko et al., J. Mol. Biol. 295 (2000) 997). Here we present solid-state NMR studies of PrP89-143(P101L) fibrils, probing the conformation of residues in the hydrophobic segment 112-124 with chemical shifts. The conformations of glycine residues were analyzed using doubly C-13 = 0 labeled peptides by two-dimensional (2D) double-quantum correlation, and double-quantum filtered dephasing distance measurements. MQ-NMR experiments were carried out to probe the relative alignment of the individual peptides fibrils. These NMR studies indicate that the 112-124 segment adopts an extended beta-sheet conformation, though not in a parallel, in register alignment. There is evidence for conformational variability at Gly 113. DQ correlation experiments provide useful information in regions with conformational heterogeneity. (c) 2005 Elsevier Inc. All rights reserved.

}, keywords = {identification}, isbn = {0926-2040}, doi = {Doi 10.1016/J.Ssnmr.2005.09.017}, url = {://WOS:000234417500020}, author = {Lim, K. H. and Nguyen, T. N. and Damo, S. M. and Mazur, T. and Ball, H. L. and Prusiner, S. B. and Pines, A. and Wemmer, D. E.} } @article {305, title = {Toward ex situ phase-encoded spectroscopic imaging}, journal = {Concepts in Magnetic Resonance Part B-Magnetic Resonance Engineering}, volume = {29B}, year = {2006}, note = {Concept Magn Reson B067JNTimes Cited:7Cited References Count:20}, month = {Aug}, pages = {137-144}, abstract = {

Spectroscopic imaging of a sample placed outside of both the radio frequency and the imaging gradient coils is presented. The sample is placed in a field with a permanent one-dimensional inhomogeneity. The imaging gradients used for phase encoding are designed to produce a static field that depends only on the transverse direction, uncoupling the effects associated with the single-sided nature of these coils. Two-dimensional imaging coupled with chemical shift information is obtained via the ex situ matching technique. Open-saddle geometry is used to match the static field profile for chemical shift information recovery. (C) 2006 Wiley Periodicals, Inc.

}, keywords = {probe}, isbn = {1552-5031}, doi = {Doi 10.1002/Cmr.B.20069}, url = {://WOS:000239298100004}, author = {Demas, V. and Meriles, C. and Sakellariou, D. and Han, S. I. and Reimer, J. and Pines, A.} } @article {313, title = {Distinguishing multiple chemotaxis Y protein conformations with laser-polarized Xe-129 NMR}, journal = {Protein Science}, volume = {14}, year = {2005}, note = {Protein Sci907SSTimes Cited:23Cited References Count:27}, month = {Apr}, pages = {848-855}, abstract = {

The chemical shift of the Xe-129 NMR signal has been shown to be extremely sensitive to the local environment around the atom and has been used to follow processes such as ligand binding by bacterial periplasmic binding proteins. Here we show that the Xe-129 shift can sense more subtle changes: magnesium binding, BeF3- activation, and peptide binding by the Escherichia coli chemotaxis Y protein. H-1-N-15 correlation spectroscopy and X-ray crystallography were used to identify two xenon-binding cavities in CheY that are primarily responsible for the shift changes. One site is near the active site, and the other is near the peptide binding site.

}, keywords = {cavity}, isbn = {0961-8368}, doi = {Doi 10.1110/Ps.041231005}, url = {://WOS:000227738900002}, author = {Lowery, T. J. and Doucleff, M. and Ruiz, E. J. and Rubin, S. M. and Pines, A. and Wemmer, D. E.} } @article {308, title = {High-resolution NMR spectroscopy with a portable single-sided sensor}, journal = {Science}, volume = {308}, year = {2005}, note = {Science931JTTimes Cited:89Cited References Count:7}, month = {May 27}, pages = {1279-1279}, keywords = {fields}, isbn = {0036-8075}, doi = {Doi 10.1126/Science.1108944}, url = {://WOS:000229482300037}, author = {Perlo, J. and Demas, V. and Casanova, F. and Meriles, C. A. and Reimer, J. and Pines, A. and Blumich, B.} } @article {320, title = {Xenon NMR as a probe for microporous and mesoporous solids, polymers, liquid crystals, solutions, flames, proteins, imaging}, journal = {Actualite Chimique}, year = {2005}, note = {Actual ChimiqueSuppl. 287952GHTimes Cited:3Cited References Count:89}, month = {Jun}, pages = {16-34}, abstract = {

We present in this paper some examples of the applications of the Nuclear Magnetic Resonance (NMR) of xenon used as a probe in the study of different chemical environments: determination of the porosity of micro-and mesoporous solids, evaluation of the concentrations and sizes of amorphous domains in solid polymers, characterization of liquid crystals, study of combustion processes at high temperature, determination of the structure and dynamics of organic systems and proteins in solution, assessment of cerebral blood flow.

}, keywords = {silica-gels}, isbn = {0151-9093}, url = {://WOS:000230991500005}, author = {Bartik, K. and Choquet, P. and Constantinesco, A. and Duhamel, G. and Fraissard, J. and Hyacinthe, J. N. and Jokisaari, J. and Locci, E. and Lowery, T. J. and Luhmer, M. and Meersmann, T. and Moudrakovski, I. L. and Pavlovskaya, G. E. and Pierce, K. L. and Pines, A. and Ripmeester, J. A. and Telkki, V. V. and Veeman, W. S.} } @article {310, title = {Zero- to low-field MRI with averaging of concomitant gradient fields}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {102}, year = {2005}, note = {P Natl Acad Sci USA898JKTimes Cited:18Cited References Count:22}, month = {Feb 8}, pages = {1840-1842}, abstract = {

Magnetic resonance imaging (MRI) encounters fundamental limits in circumstances in which the static magnetic field is not sufficiently strong to truncate unwanted, so-called concomitant components of the gradient field. This limitation affects the attainable optimal image fidelity and resolution most prominently in low-field imaging. in this article, we introduce the use of pulsed magnetic-field averaging toward relaxing these constraints. It is found that the image of an object can be retrieved by pulsed low fields in the presence of the full spatial variation of the imaging encoding gradient field even in the absence of the typical uniform high-field time-independent contribution. In addition, error-compensation schemes can be introduced through the application of symmetrized pulse sequences. Such schemes substantially mitigate artifacts related to evolution in strong magnetic-field gradients, magnetic fields that vary in direction and orientation, and imperfections of the applied field pulses.

}, keywords = {selection}, isbn = {0027-8424}, doi = {Doi 10.1073/Pnas.0409115102}, url = {://WOS:000227072900009}, author = {Meriles, C. A. and Sakellariou, D. and Trabesinger, A. H. and Demas, V. and Pines, A.} } @article {336, title = {Three-dimensional phase-encoded chemical shift MRI in the presence of inhomogeneous fields}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {101}, year = {2004}, note = {P Natl Acad Sci USA830EQTimes Cited:18Cited References Count:12}, month = {Jun 15}, pages = {8845-8847}, abstract = {

A pulse sequence consisting of an excitation pulse and two adiabatic full-passage pulses with scaled relative peak amplitudes is combined with phase encoding to recover chemical shift information within 3D images in a 1D inhomogeneous static magnetic field with a matched rf field gradient. The results are discussed in the context of ex situ magnetic resonance and imaging. The future directions of our research in implementing the ex situ technique in a real one-sided system are also discussed.

}, keywords = {pulses}, isbn = {0027-8424}, doi = {Doi 10.1073/Pnas.0403016101}, url = {://WOS:000222104900004}, author = {Demas, V. and Sakellariou, D. and Meriles, C. A. and Han, S. and Reimer, J. and Pines, A.} } @article {367, title = {Detection of a conformational change in maltose binding protein by Xe-129 NMR spectroscopy}, journal = {Journal of the American Chemical Society}, volume = {123}, year = {2001}, note = {J Am Chem Soc467XNTimes Cited:28Cited References Count:28}, month = {Sep 5}, pages = {8616-8617}, keywords = {blood}, isbn = {0002-7863}, doi = {Doi 10.1021/Ja0110325}, url = {://WOS:000170729200029}, author = {Rubin, S. M. and Spence, M. M. and Dimitrov, I. E. and Ruiz, E. J. and Pines, A. and Wemmer, D. E.} } @article {364, title = {Functionalized xenon as a biosensor}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {98}, year = {2001}, note = {P Natl Acad Sci USA472CZTimes Cited:112Cited References Count:29}, month = {Sep 11}, pages = {10654-10657}, abstract = {

The detection of biological molecules and their interactions is a significant component of modern biomedical research. In current biosensor technologies, simultaneous detection is limited to a small number of analytes by the spectral overlap of their signals. We have developed an NMR-based xenon biosensor that capitalizes on the enhanced signal-to-noise, spectral simplicity, and chemical-shift sensitivity of laser-polarized xenon to detect specific biomolecules at the level of tens of nanomoles. We present results using xenon \"functionalized\" by a biotin-modified supramolecular cage to detect biotin-avidin binding. This biosensor methodology can be extended to a multiplexing assay for multiple analytes.

}, keywords = {mri}, isbn = {0027-8424}, doi = {Doi 10.1073/Pnas.191368398}, url = {://WOS:000170966800030}, author = {Spence, M. M. and Rubin, S. M. and Dimitrov, I. E. and Ruiz, E. J. and Wemmer, D. E. and Pines, A. and Yao, S. Q. and Tian, F. and Schultz, P. G.} } @article {382, title = {High-T-c SQUIDs for low-field NMR and MRI of room temperature samples}, journal = {Ieee Transactions on Applied Superconductivity}, volume = {9}, year = {1999}, note = {Ieee T Appl SuperconPart 3225MCTimes Cited:5Cited References Count:18}, month = {Jun}, pages = {4424-4427}, abstract = {

We have constructed a high-T-c SQUID spectrometer to detect NMR signals from samples at room temperature in magnetic fields up to 3 mT. The multiloop SQUID magnetometer has a system noise of about 30 fT/Hz(1/2) at the relevant frequencies of 2 to 100 kHz, The magnetometer is operated in vacuum at 77 K, and is separated from the sample, which is less than 1.5 mm away, by a sapphire window, In a magnetic field of 2 mT we can detect the proton spin echo at 86 kHz without signal averaging. This sensitivity enables us to obtain one-dimensional images. In addition, we present data on hyperpolarized Xe-129, which has an optically pumped polarization of several percent.

}, keywords = {frequencies}, isbn = {1051-8223}, doi = {Doi 10.1109/77.784006}, url = {://WOS:000081964500386}, author = {Schlenga, K. and McDermott, R. F. and Clarke, J. and de Souza, R. E. and Wong-Foy, A. and Pines, A.} } @article {383, title = {Low-field magnetic resonance imaging with a high-T-c dc superconducting quantum interference device}, journal = {Applied Physics Letters}, volume = {75}, year = {1999}, note = {Appl Phys Lett259URTimes Cited:49Cited References Count:19}, month = {Dec 6}, pages = {3695-3697}, abstract = {

A spectrometer incorporating a high transition temperature dc superconducting quantum interference device (SQUID) is used to obtain nuclear magnetic resonance signals from protons in mineral oil at room temperature in fields up to 3 mT. The spatial separation between the SQUID magnetometer at 77 K and the sample at room temperature is less than 1 mm. At 2 mT, the signal is easily resolved in a single scan. Two-dimensional images of samples consisting of pieces of lucite or glass immersed in mineral oil are obtained at 2 mT. (C) 1999 American Institute of Physics. [S0003-6951(99)03649-9].

}, keywords = {mri}, isbn = {0003-6951}, doi = {Doi 10.1063/1.125432}, url = {://WOS:000083912800035}, author = {Schlenga, K. and McDermott, R. and Clarke, J. and de Souza, R. E. and Wong-Foy, A. and Pines, A.} } @article {387, title = {NMR and MRI obtained with high transition temperature DC SQUIDs}, journal = {Journal of the Brazilian Chemical Society}, volume = {10}, year = {1999}, note = {J Brazil Chem Soc259BETimes Cited:11Cited References Count:30}, month = {Jul-Aug}, pages = {307-312}, abstract = {

We have measured nuclear magnetic resonance (NMR) signals from several samples at room temperature in magnetic fields ranging from about 0.05 mT to 2 mT using a spectrometer based on a high-T-c de SQUID (high transition temperature de Superconducting QUantum Interference Device). We are able to observe proton signals from 1 mL of mineral oil in 2 mT in a single transient. The sensitivity of this system has also allowed the detection of proton NMR at magnetic fields as low as 0.059 mT, which is comparable to the Earth\&$\#$39;s field. Such results make possible a number of new experiments in magnetic resonance imaging (MRI). We present a two-dimensional image of a phantom filled with mineral oil obtained in a field of 2 mT.

}, keywords = {system}, isbn = {0103-5053}, url = {://WOS:000083873500009}, author = {de Souza, R. E. and Schlenga, K. and Wong-Foy, A. and McDermott, R. and Pines, A. and Clarke, J.} } @article {379, title = {NMR study of InP quantum dots: Surface structure and size effects}, journal = {Journal of Chemical Physics}, volume = {110}, year = {1999}, note = {J Chem Phys192HUTimes Cited:30Cited References Count:28}, month = {May 8}, pages = {8861-8864}, abstract = {

We report the results of P-31 NMR measurements on trioctylphosphine oxide (TOPO) passivated InP quantum dots. The spectra show distinct surface-capping sites, implying a manifold of crystal-ligand bonding configurations. Two In P-31 surface components are resolved and related to different electronic surroundings. With decreasing particle size the In P-31 core resonance reveals an increasing upfield chemical shift related to the overall size dependence of the InP electronic structure. (C) 1999 American Institute of Physics. [S0021-9606(99)70718-X].

}, keywords = {clusters}, isbn = {0021-9606}, doi = {Doi 10.1063/1.478858}, url = {://WOS:000080073200002}, author = {Tomaselli, M. and Yarger, J. L. and Bruchez, M. and Havlin, R. H. and deGraw, D. and Pines, A. and Alivisatos, A. P.} } @article {393, title = {Effects of diffusion on magnetic resonance imaging of laser-polarized xenon gas}, journal = {Journal of Chemical Physics}, volume = {108}, year = {1998}, note = {J Chem PhysZh114Times Cited:30Cited References Count:24}, month = {Apr 15}, pages = {6233-6239}, abstract = {

Molecular diffusion during the application of magnetic field gradients can distort magnetic resonance images. A systematic characterization of these distortions in one dimension was performed using highly spin-polarized xenon gas. By varying the strength of the applied gradient and the geometric dimension of the sample, the evolution of these image distortions between the regimes of strong and weak diffusion was observed. These results are compared with numerical simulations. By directly measuring the displacement distribution of the polarized xenon atoms, it is shown that in the weak-diffusion regime the image distortions originate from the restricted diffusive motion near the sample boundaries, in agreement with previous theoretical work. Additionally, it is shown that the effects of diffusion can be utilized to enhance the contrast between the boundaries and bulk in the images of polarized gas samples, and thus may be exploited as a means of boundary detection in such systems. (C) 1998 American Institute of Physics. [S0021-9606(98)02915-8].

}, keywords = {xe-129}, isbn = {0021-9606}, doi = {Doi 10.1063/1.476030}, url = {://WOS:000073073700018}, author = {Song, Y. Q. and Goodson, B. M. and Sheridan, B. and de Swiet, T. M. and Pines, A.} } @article {402, title = {A high-resolution(17)O NMR study of siliceous zeolite faujasite}, journal = {Journal of the American Chemical Society}, volume = {120}, year = {1998}, note = {J Am Chem SocZj097Times Cited:66Cited References Count:19}, month = {Apr 15}, pages = {3510-3511}, keywords = {workstation computers}, isbn = {0002-7863}, doi = {Doi 10.1021/Ja9743001}, url = {://WOS:000073179200032}, author = {Bull, L. M. and Cheetham, A. K. and Anupold, T. and Reinhold, A. and Samoson, A. and Sauer, J. and Bussemer, B. and Lee, Y. and Gann, S. and Shore, J. and Pines, A. and Dupree, R.} } @article {400, title = {In situ NMR analysis of fluids contained in sedimentary rock}, journal = {Journal of Magnetic Resonance}, volume = {133}, year = {1998}, note = {J Magn Reson116WNTimes Cited:23Cited References Count:23}, month = {Aug}, pages = {385-387}, abstract = {

Limitations of resolution and absorption in standard chemical spectroscopic techniques have made it difficult to study fluids in sedimentary rocks. In this paper, we show that a chemical characterization of pore fluids may be obtained in situ by magic angle spinning (MAS) nuclear magnetic resonance (NMR), which is normally used for solid samples. H-1 MAS-NMR spectra of water and crude oil in Berea sandstone show sufficient chemical shift resolution for a straightforward determination of the oil/water ratio, (C) 1998 Academic Press.

}, keywords = {oil}, isbn = {1090-7807}, doi = {Doi 10.1006/Jmre.1998.1459}, url = {://WOS:000075748200020}, author = {de Swiet, T. M. and Tomaselli, M. and Hurlimann, M. D. and Pines, A.} } @article {399, title = {NMR spectra with peaks at the principal values of the chemical shielding tensor}, journal = {Chemical Physics Letters}, volume = {285}, year = {1998}, note = {Chem Phys LettZf354Times Cited:10Cited References Count:25}, month = {Mar 13}, pages = {59-63}, abstract = {

The NMR chemical shielding in a solid powder sample produces featured, but broad, lineshapes, or powder patterns, because the shielding experienced by a nuclear spin depends on the spatial orientation of its local molecular frame with respect to the external magnetic field. The Lineshape, however, is fully determined by the three principal values of the shielding tenser. We present a simple approach that uses sample spinning NMR to extract peaks at the principal-value frequencies from chemical shielding powder patterns. Such techniques may simplify spectra with overlapping powder patterns without the information loss inherent in fast magic angle spinning. Experimental data and numerical simulations are presented for two P-31 model compounds. (C) 1998 Elsevier Science B.V.

}, keywords = {SPECTROSCOPY}, isbn = {0009-2614}, doi = {Doi 10.1016/S0009-2614(97)01478-4}, url = {://WOS:000072889100010}, author = {de Swiet, T. M. and Tomaselli, M. and Pines, A.} } @article {401, title = {Reversal of radio-frequency-driven spin diffusion by reorientation of the sample spinning axis}, journal = {Journal of Chemical Physics}, volume = {108}, year = {1998}, note = {J Chem PhysYr359Times Cited:9Cited References Count:39}, month = {Jan 15}, pages = {826-829}, abstract = {

The dipolar Hamiltonian in a rapidly rotating sample is scaled by the second Legendre polynomial of the cosine of the angle between the rotation axis and the static magnetic field. It is, therefore, possible to refocus the spatial polarization-transfer process, often termed spin diffusion, in extended spin systems by reorienting the rotor axis such that the dipolar interaction Hamiltonian changes sign. We present experimental results which demonstrate that a rapid mechanical sample reorientation leads to a time reversal of the \"radio-frequency-driven\" spin diffusion among C-13 spins. (C) 1998 American Institute of Physics. [S0021-9606(98)03503-X].

}, keywords = {echoes}, isbn = {0021-9606}, doi = {Doi 10.1063/1.475494}, url = {://WOS:000071487500002}, author = {De Paul, S. M. and Tomaselli, M. and Pines, A. and Ernst, M. and Meier, B. H.} } @article {391, title = {Scalar and anisotropic J interactions in undoped InP: A triple-resonance NMR study}, journal = {Physical Review B}, volume = {58}, year = {1998}, note = {Phys Rev B125HUTimes Cited:29Cited References Count:40}, month = {Oct 1}, pages = {8627-8633}, abstract = {

The heteronuclear J-coupling tensor between nearest neighbor P-31 and In-113 spins in undoped InP is investigated by means of In-113--\>P-31 polarization transfer under rapid magic angle spinning (MAS). The scalar contribution can be measured directly and is found to have the value \J(iso)(P-31-In-113,In-115)\ = (225+/-10) Hz. The principal value of the traceless anisotropic J-coupling tensor (pseudodipolar coupling) is determined to be J(aniso)(P-31-In-113,In-115)= 2/3[J(parallel to)(P-31-In-113,In-115)-J(perpendicular to)(P-31-In-113,In-115)] = (813+/-50) or (1733+/-50) Hz, assuming axial symmetry with the principal axis parallel to the In-P bond. Our values deviate from those reported previously [M. Engelsberg and R. E. Norberg, Phys. Rev. B 5, 3395 (1972)] [based on a moment analysis of the P-31 resonance \J(iso)(31P-In-113,In-115)\ = 350 Hz and J(aniso)(P-31-In-113,In-115) = 1273 Hz], but confirm the postulate that the nearest neighbor P-31-In-113,In-115 magnetic dipolar and pseudodipolar interactions are of the same order of magnitude and partially cancel each other.

}, keywords = {solids}, isbn = {0163-1829}, doi = {Doi 10.1103/Physrevb.58.8627}, url = {://WOS:000076232100075}, author = {Tomaselli, M. and deGraw, D. and Yarger, J. L. and Augustine, M. P. and Pines, A.} } @article {421, title = {Cross-polarization from quadrupolar nuclei to silicon using low-radio-frequency amplitudes during magic-angle spinning}, journal = {Journal of Physical Chemistry B}, volume = {101}, year = {1997}, note = {J Phys Chem BWu630Times Cited:51Cited References Count:50}, month = {Apr 17}, pages = {3240-3249}, abstract = {

The dynamics of cross-polarization from the central transition of a quadrupolar nucleus (Al-27 or Na-23) to a spin-1/2 nucleus (Si-29) during magic-angle spinning and using low-radio-frequency Geld strengths are analyzed for the mineral low albite. Under these conditions additional complications in the spin-lock behavior of the quadrupolar nucleus and in the cross-polarization process were found experimentally and are examined in detail. A step-by-step procedure for optimizing cross-polarization from the central transition of a quadrupolar nucleus to a spin-1/2 nucleus is described. Significant enhancement of Si-29 NMR sensitivity and several applications are demonstrated.

}, keywords = {locking}, isbn = {1089-5647}, doi = {Doi 10.1021/Jp9623711}, url = {://WOS:A1997WU63000031}, author = {DePaul, S. M. and Ernst, M. and Shore, J. S. and Stebbins, J. F. and Pines, A.} } @article {494, title = {Adsorption Effects in Aluminophosphate Molecular-Sieves Studied by Al-27 Double-Rotation Nmr}, journal = {Catalysis Letters}, volume = {15}, year = {1992}, note = {Catal LettJj259Times Cited:18Cited References Count:17}, pages = {65-73}, abstract = {

Al-27 double rotation NMR (DOR) spectroscopy is used to investigate structural changes in the framework of several aluminophosphate molecular sieves upon adsorption of water. The shapes, widths, and positions of the spectral lines yield information on the aluminum environments, adsorption sites, and degree of structural disorder undergone upon water adsorption.

}, keywords = {alpo4-8}, isbn = {1011-372X}, doi = {Doi 10.1007/Bf00770899}, url = {://WOS:A1992JJ25900008}, author = {Jelinek, R. and Chmelka, B. F. and Wu, Y. and Davis, M. E. and Ulan, J. G. and Gronsky, R. and Pines, A.} } @conference {509, title = {Framework ordering in aluminophosphate molecular sieves studied by (27)Al double rotation NMR}, volume = {69}, year = {1991}, month = {1991}, pages = {435-442}, publisher = {Elsevier}, organization = {Elsevier}, author = {Chmelka, B.F. and Wu, Y. and Jelinek, R. and Davis, M.E. and Pines, A.}, editor = {P.A. Jacobs, N.I. Jaeger, L. Kubelkova, and B. Wichterlov} } @article {510, title = {Measurement of Xenon Distribution Statistics in Na-a Zeolite Cavities}, journal = {Physical Review Letters}, volume = {66}, year = {1991}, note = {Phys Rev LettEv897Times Cited:78Cited References Count:21}, month = {Feb 4}, pages = {580-583}, abstract = {

Xe-129 NMR spectroscopy has been used to probe directly the distribution of xenon atoms confined in atomic-size Na-A zeolite cavities. For mean xenon occupancies less than about three Xe atoms per a-cage, the guest populations are well described by binomial statistics. At higher guest loadings the finite volumes of the xenon atoms become significant, as reflected by a fit of the experimental populations with a hypergeometric distribution, with a maximum of seven Xe atoms per cage. At the highest xenon loadings the experimental distribution is narrower than hypergeometric, as predicted by Monte Carlo simulations.

}, keywords = {fluids}, isbn = {0031-9007}, doi = {Doi 10.1103/Physrevlett.66.580}, url = {://WOS:A1991EV89700016}, author = {Chmelka, B. F. and Raftery, D. and Mccormick, A. V. and Demenorval, L. C. and Levine, R. D. and Pines, A.} } @article {511, title = {Nmr-Study of the Distribution of Aromatic-Molecules in Nay Zeolite}, journal = {Journal of Physical Chemistry}, volume = {95}, year = {1991}, note = {J Phys Chem-UsEr473Times Cited:70Cited References Count:64}, month = {Jan 10}, pages = {303-310}, abstract = {

Local and macroscopic distributions of adsorbed benzene, 1,3,5-trimethylbenzene, and hexamethylbenzene (HMB) molecules among the intracrystalline of NaY zeolite samples have been investigated by Xe-129 and multiple-quantum NMR. Xenon-129 NMR, a sensitive probe of macroscopic distributions of molecules in zeolites at room temperature, demonstrates the importance of sample heat treatment in distributing an adsorbate homogeneously throughout a collection of zeolite particles. NaY samples containing organic guests adsorbed a temperatures near the bulk species\&$\#$39; melting point produce multiple or broad xenon lines characteristic of macroscopic (i.e., interparticle) adsorbate concentration gradients. After thorough heat treatment of the samples at elevated temperatures, the xenon spectrum collapses to a single sharp line, consistent with a macroscopically uniform distribution. For HMB adsorbed in NaY, \"counting\" hydrogen clusters by multiple-quantum NMR reveals intraparticle HMB distributions consistent with one molecular per cavity at low loadings (average bulk loading less-than-or-equal-to 1 molecule per cavity) and two molecules per cavity at higher loadings.

}, keywords = {catalysts}, isbn = {0022-3654}, doi = {Doi 10.1021/J100154a056}, url = {://WOS:A1991ER47300056}, author = {Chmelka, B. F. and Pearson, J. G. and Liu, S. B. and Ryoo, R. and Demenorval, L. C. and Pines, A.} } @article {515, title = {High-Resolution Al-27 Nmr-Spectroscopy of the Aluminophosphate Molecular-Sieve Vpi-5}, journal = {Nature}, volume = {346}, year = {1990}, note = {NatureDt679Times Cited:97Cited References Count:12}, month = {Aug 9}, pages = {550-552}, isbn = {0028-0836}, doi = {Doi 10.1038/346550a0}, url = {://WOS:A1990DT67900067}, author = {Wu, Y. and Chmelka, B. F. and Pines, A. and Davis, M. E. and Grobet, P. J. and Jacobs, P. A.} } @article {523, title = {Investigations of Adsorbed Organic-Molecules in Na-Y Zeolite by Xe-129 Nmr}, journal = {Journal of Physical Chemistry}, volume = {94}, year = {1990}, note = {J Phys Chem-UsCh532Times Cited:61Cited References Count:26}, month = {Jan 11}, pages = {27-31}, isbn = {0022-3654}, doi = {Doi 10.1021/J100364a006}, url = {://WOS:A1990CH53200006}, author = {Demenorval, L. C. and Raftery, D. and Liu, S. B. and Takegoshi, K. and Ryoo, R. and Pines, A.} } @inbook {555, title = {Calcination-dependence ofplatinum cluster formation in NaY zeolite: A xenon-129 NMR study}, booktitle = {Structure and Reactivity of Surfaces}, year = {1989}, pages = {269-278}, publisher = {Elsevier Science Publishers}, organization = {Elsevier Science Publishers}, address = {Amsterdam}, author = {Chmelka, B.F. and de Menorval, L.C. and Csencsits, R. and Ryoo, R. and Liu, S.B. and Radke, C.J. and Petersen, E.E. and Pines, A.}, editor = {C. Morterra, A. Zecchina, and G. Costa} } @article {559, title = {Broad-Band Heteronuclear Spin Decoupling in Solids}, journal = {Chemical Physics Letters}, volume = {144}, year = {1988}, note = {Chem Phys LettM4326Times Cited:19Cited References Count:11}, month = {Mar 4}, pages = {324-327}, isbn = {0009-2614}, doi = {Doi 10.1016/0009-2614(88)87122-7}, url = {://WOS:A1988M432600002}, author = {Suter, D. and Pines, A. and Lee, J. H. and Drobny, G.} } @article {569, title = {Probing Metal Cluster Formation in Nay Zeolite by Xe-129 Nmr}, journal = {Journal of the American Chemical Society}, volume = {110}, year = {1988}, note = {J Am Chem SocP0739Times Cited:33Cited References Count:18}, month = {Jun 22}, pages = {4465-4467}, isbn = {0002-7863}, doi = {Doi 10.1021/Ja00221a086}, url = {://WOS:A1988P073900086}, author = {Chmelka, B. F. and Ryoo, R. and Liu, S. B. and Demenorval, L. C. and Radke, C. J. and Petersen, E. E. and Pines, A.} } @article {583, title = {Distribution of Hexamethylbenzene in a Zeolite Studied by Xe-129 and Multiple-Quantum Nmr}, journal = {Journal of Physical Chemistry}, volume = {91}, year = {1987}, note = {J Phys Chem-UsL6632Times Cited:63Cited References Count:16}, month = {Dec 31}, pages = {6575-6577}, isbn = {0022-3654}, doi = {Doi 10.1021/J100311a003}, url = {://WOS:A1987L663200003}, author = {Ryoo, R. and Liu, S. B. and Demenorval, L. C. and Takegoshi, K. and Chmelka, B. and Trecoske, M. and Pines, A.} } @article {610, title = {Multiple Quantum Spectrum of Oriented Hexane-D6}, journal = {Chemical Physics}, volume = {108}, year = {1986}, note = {Chem PhysE1754Times Cited:7Cited References Count:27}, month = {Oct 1}, pages = {179-185}, isbn = {0301-0104}, doi = {Doi 10.1016/0301-0104(86)85039-X}, url = {://WOS:A1986E175400001}, author = {Drobny, G. and Weitekamp, D. P. and Pines, A.} } @article {656, title = {Selectivity in Multiple-Quantum Spectroscopy}, journal = {Philosophical Transactions of the Royal Society a-Mathematical Physical and Engineering Sciences}, volume = {299}, year = {1981}, note = {Philos T R Soc ALj669Times Cited:19Cited References Count:17}, pages = {585-592}, isbn = {1364-503X}, doi = {Doi 10.1098/Rsta.1981.0036}, url = {://WOS:A1981LJ66900008}, author = {Drobny, G. and Pines, A. and Sinton, S. and Warren, W. S. and Weitekamp, D. P.} } @article {679, title = {Fourier transform multiple quantum nuclear magnetic resonance}, journal = {Faraday Symposia of the Chemical Society}, volume = {13}, year = {1978}, pages = {49-55}, abstract = {

The excitation and detection of multiple quantum transitions in systems of coupled spins offers, among other advantages, an increase in resolution over single quantum n.m.r. since the number of lines decreases as the order of the transition increases. This paper reviews the motivation for detecting multiple quantum transitions by a Fourier transform experiment and describes an experimental approach to high resolution multiple quantum spectra in dipolar systems along with results on some protonated liquid crystal systems. A simple operator formalism for the essential features of the time development is presented and some applications in progress are discussed.

}, isbn = {0301-5696}, url = {http://dx.doi.org/10.1039/FS9781300049}, author = {Drobny, Gary and Pines, Alexander and Sinton, Steven and Weitekamp, Daniel P. and Wemmer, David} }