@article {245,
	title = {Fundamental Aspects of Parahydrogen Enhanced Low-Field Nuclear Magnetic Resonance},
	journal = {Physical Review Letters},
	volume = {110},
	year = {2013},
	note = {Phys Rev Lett113RITimes Cited:0Cited References Count:28},
	month = {Mar 26},
	pages = {137602},
	abstract = {<p>We report new phenomena in low-field H-1 nuclear magnetic resonance (NMR) spectroscopy using parahydrogen induced polarization (PHIP), enabling determination of chemical shift differences, delta nu, and the scalar coupling constant J. NMR experiments performed with thermal polarization in millitesla magnetic fields do not allow the determination of scalar coupling constants for homonuclear coupled spins in the inverse weak coupling regime (delta nu \&lt; J). We show here that low-field PHIP experiments in the inverse weak coupling regime enable the precise determination of delta nu and J. Furthermore we experimentally prove that observed splittings are related to delta nu in a nonlinear way. Naturally abundant C-13 and Si-29 isotopes lead to heteronuclear J-coupled H-1-multiplet lines with amplitudes significantly enhanced compared to the amplitudes for thermally prepolarized spins. PHIP-enhanced NMR in the millitesla regime allows us to measure characteristic NMR parameters in a single scan using samples containing rare spins in natural abundance. DOI: 10.1103/PhysRevLett.110.137602</p>
},
	keywords = {exchange},
	isbn = {0031-9007},
	doi = {Doi 10.1103/Physrevlett.110.137602},
	url = {<Go to ISI>://WOS:000316685100032},
	author = {Colell, J. and Turschmann, P. and Gloggler, S. and Schleker, P. and Theis, T. and Ledbetter, M. and Budker, D. and Pines, A. and Blumich, B. and Appelt, S.}
}
@article {256,
	title = {Relaxivity of Gadolinium Complexes Detected by Atomic Magnetometry},
	journal = {Magnetic Resonance in Medicine},
	volume = {66},
	year = {2011},
	note = {Magn Reson Med799AVTimes Cited:1Cited References Count:23},
	month = {Aug},
	pages = {605-608},
	abstract = {<p>Laser atomic magnetomeby is a portable and low-cost yet highly sensitive method for low magnetic field detection. In this work, the atomic magnetometer was used in a remote-detection geometry to measure the relaxivity of aqueous gadolinium-diethylenetriamine pentaacetic acid Gd(DTPA) at the Earth\&$\#$39;s magnetic field (40 mu T). The measured relaxivity of 9.7 +/- 2.0 s(-1) mM(-1) is consistent with field-cycling experiments measured at slightly higher magnetic fields, but no cryogens or strong and homogeneous magnetic field were required for this experiment. The field-independent sensitivity of 80 fT Hz(-1/2) allowed an in vitro detection limit of similar to 10 mu M Gd(DTPA) to be measured in aqueous buffer solution. The low detection limit and enhanced relaxivity of Gd-containing complexes at Earth\&$\#$39;s field motivate continued development of atomic magnetometry toward medical applications. Magn Reson Med 66:605-608, 2011. (C) 2011 Wiley-Liss, Inc.</p>
},
	keywords = {nmr},
	isbn = {0740-3194},
	doi = {Doi 10.1002/Mrm.22811},
	url = {<Go to ISI>://WOS:000293256800033},
	author = {Michalak, D. J. and Xu, S. J. and Lowery, T. J. and Crawford, C. W. and Ledbetter, M. and Bouchard, L. S. and Wemmer, D. E. and Budker, D. and Pines, A.}
}
