@article {272,
	title = {Picomolar sensitivity MRI and photoacoustic imaging of cobalt nanoparticles},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {106},
	year = {2009},
	note = {P Natl Acad Sci USA420HDTimes Cited:43Cited References Count:41},
	month = {Mar 17},
	pages = {4085-4089},
	abstract = {<p>Multimodality imaging based on complementary detection principles has broad clinical applications and promises to improve the accuracy of medical diagnosis. This means that a tracer particle advantageously incorporates multiple functionalities into a single delivery vehicle. In the present work, we explore a unique combination of MRI and photoacoustic tomography (PAT) to detect picomolar concentrations of nanoparticles. The nanoconstruct consists of ferromagnetic (Co) particles coated with gold (Au) for biocompatibility and a unique shape that enables optical absorption over a broad range of frequencies. The end result is a dual-modality probe useful for the detection of trace amounts of nanoparticles in biological tissues, in which MRI provides volume detection, whereas PAT performs edge detection.</p>
},
	keywords = {cancer},
	isbn = {0027-8424},
	doi = {Doi 10.1073/Pnas.0813019106},
	url = {<Go to ISI>://WOS:000264278800008},
	author = {Bouchard, L. S. and Anwar, M. S. and Liu, G. L. and Hann, B. and Xie, Z. H. and Gray, J. W. and Wang, X. D. and Pines, A. and Chen, F. F.}
}
@article {290,
	title = {Para-hydrogen-enhanced hyperpolarized gas-phase magnetic resonance imaging},
	journal = {Angewandte Chemie-International Edition},
	volume = {46},
	year = {2007},
	note = {Angew Chem Int Edit174ZPTimes Cited:28Cited References Count:37},
	pages = {4064-4068},
	keywords = {he-3},
	isbn = {1433-7851},
	doi = {Doi 10.1002/Anie.200700830},
	url = {<Go to ISI>://WOS:000246981900008},
	author = {Bouchard, L. S. and Kovtunov, K. V. and Burt, S. R. and Anwar, M. S. and Koptyug, I. V. and Sagdeev, R. Z. and Pines, A.}
}
@article {285,
	title = {Para-hydrogen-induced polarization in heterogeneous hydrogenation reactions},
	journal = {Journal of the American Chemical Society},
	volume = {129},
	year = {2007},
	note = {J Am Chem Soc160MRTimes Cited:36Cited References Count:45},
	month = {May 2},
	pages = {5580-5586},
	abstract = {<p>We demonstrate the creation and observation of para-hydrogen-induced polarization in heterogeneous hydrogenation reactions. Wilkinson\&$\#$39;s catalyst, RhCl(PPh3)(3), supported on either modified silica gel or a polymer, is shown to hydrogenate styrene into ethylbenzene and to produce enhanced spin polarizations, observed through NMR, when the reaction was performed with H-2 gas enriched in the para spin isomer. Furthermore, gaseous phase para-hydrogenation of propylene to propane with two catalysts, the Wilkinson\&$\#$39;s catalyst supported on modified silica gel and Rh(cod)(sulfos) (cod = cycloocta-1,5-diene; sulfos = -O3S(C6H4)CH2C(CH2PPh2)(3)) supported on silica gel, demonstrates heterogeneous catalytic conversion resulting in large spin polarizations. These experiments serve as a direct verification of the mechanism of heterogeneous hydrogenation reactions involving immobilized metal complexes and can be potentially developed into a practical tool for producing catalyst-free fluids with highly polarized nuclear spins for a broad range of hyperpolarized NMR and MRI applications.</p>
},
	keywords = {alignment},
	isbn = {0002-7863},
	doi = {Doi 10.1021/Ja068653o},
	url = {<Go to ISI>://WOS:000245946400064},
	author = {Koptyug, I. V. and Kovtunov, K. V. and Burt, S. R. and Anwar, M. S. and Hilty, C. and Han, S. I. and Pines, A. and Sagdeev, R. Z.}
}
