@article {282,
	title = {NMR imaging of catalytic hydrogenation in microreactors with the use of para-hydrogen},
	journal = {Science},
	volume = {319},
	year = {2008},
	note = {Science254HBTimes Cited:55Cited References Count:33},
	month = {Jan 25},
	pages = {442-445},
	abstract = {<p>Catalysis is vital to industrial chemistry, and the optimization of catalytic reactors attracts considerable resources. It has proven challenging to correlate the active regions in heterogeneous catalyst beds with morphology and to monitor multistep reactions within the bed. We demonstrate techniques, using magnetic resonance imaging and para- hydrogen ( p-H(2)) polarization, that allow direct visualization of gas- phase flow and the density of active catalyst in a packed- bed microreactor, as well as control over the dynamics of the polarized state in space and time to facilitate the study of subsequent reactions. These procedures are suitable for characterizing reactors and reactions in microfluidic devices where low sensitivity of conventional magnetic resonance would otherwise be the limiting factor.</p>
},
	keywords = {chip},
	isbn = {0036-8075},
	doi = {Doi 10.1126/Science.1151787},
	url = {<Go to ISI>://WOS:000252576600031},
	author = {Bouchard, L. S. and Burt, S. R. and Anwar, M. S. and Kovtunov, K. V. and Koptyug, I. V. and Pines, A.}
}
@article {290,
	title = {Para-hydrogen-enhanced hyperpolarized gas-phase magnetic resonance imaging},
	journal = {Angewandte Chemie-International Edition},
	volume = {46},
	year = {2007},
	note = {Angew Chem Int Edit174ZPTimes Cited:28Cited References Count:37},
	pages = {4064-4068},
	keywords = {he-3},
	isbn = {1433-7851},
	doi = {Doi 10.1002/Anie.200700830},
	url = {<Go to ISI>://WOS:000246981900008},
	author = {Bouchard, L. S. and Kovtunov, K. V. and Burt, S. R. and Anwar, M. S. and Koptyug, I. V. and Sagdeev, R. Z. and Pines, A.}
}
@article {285,
	title = {Para-hydrogen-induced polarization in heterogeneous hydrogenation reactions},
	journal = {Journal of the American Chemical Society},
	volume = {129},
	year = {2007},
	note = {J Am Chem Soc160MRTimes Cited:36Cited References Count:45},
	month = {May 2},
	pages = {5580-5586},
	abstract = {<p>We demonstrate the creation and observation of para-hydrogen-induced polarization in heterogeneous hydrogenation reactions. Wilkinson\&$\#$39;s catalyst, RhCl(PPh3)(3), supported on either modified silica gel or a polymer, is shown to hydrogenate styrene into ethylbenzene and to produce enhanced spin polarizations, observed through NMR, when the reaction was performed with H-2 gas enriched in the para spin isomer. Furthermore, gaseous phase para-hydrogenation of propylene to propane with two catalysts, the Wilkinson\&$\#$39;s catalyst supported on modified silica gel and Rh(cod)(sulfos) (cod = cycloocta-1,5-diene; sulfos = -O3S(C6H4)CH2C(CH2PPh2)(3)) supported on silica gel, demonstrates heterogeneous catalytic conversion resulting in large spin polarizations. These experiments serve as a direct verification of the mechanism of heterogeneous hydrogenation reactions involving immobilized metal complexes and can be potentially developed into a practical tool for producing catalyst-free fluids with highly polarized nuclear spins for a broad range of hyperpolarized NMR and MRI applications.</p>
},
	keywords = {alignment},
	isbn = {0002-7863},
	doi = {Doi 10.1021/Ja068653o},
	url = {<Go to ISI>://WOS:000245946400064},
	author = {Koptyug, I. V. and Kovtunov, K. V. and Burt, S. R. and Anwar, M. S. and Hilty, C. and Han, S. I. and Pines, A. and Sagdeev, R. Z.}
}
