@article {3196, title = {Hyperpolarized NMR Spectroscopy: d-DNP, PHIP, and SABRE Techniques}, journal = {Chemistry - An Aisan Journal}, volume = {13}, year = {2018}, month = {08/2018}, abstract = {

The intensity of NMR signals can be enhanced by several orders of magnitude by using various techniques for the hyperpolarization of different molecules. Such approaches can overcome the main sensitivity challenges facing modern NMR/magnetic resonance imaging (MRI) techniques, whilst hyperpolarized fluids can also be used in a variety of applications in material science and biomedicine. This Focus Review considers the fundamentals of the preparation of hyperpolarized liquids and gases by using dissolution dynamic nuclear polarization (d-DNP) and parahydrogen-based techniques, such as signal amplification by reversible exchange (SABRE) and parahydrogen-induced polarization (PHIP), in both heterogeneous and homogeneous processes. The various new aspects in the formation and utilization of hyperpolarized fluids, along with the possibility of observing NMR signal enhancement, are described.

}, doi = {10.1002/asia.201800551}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/asia.201800551}, author = {Kirill Kovtunov and Ekaterina Pokochueva and Oleg Salnikov and Samuel Cousin and Dennis Kurzbach and Basile Vuichoud and Sami Jannin and Eduard Chekmenev and Boyd Goodson and Danila Barskiy and Igor Koptyug} } @article {3195, title = {Selective Single-Site Pd-In Hydrogenation Catalyst for Production of Enhanced Magnetic Resonance Signals using Parahydrogen}, journal = {Chemistry - A European Journal}, volume = {24}, year = {2018}, month = {01/2018}, chapter = {2547}, abstract = {

Pd\−In/Al2O3\ single-site catalyst was able to show high selectivity (up to 98\ \%) in the gas phase semihydrogenation of propyne. Formation of intermetallic Pd\−In compound was studied by XPS during reduction of the catalyst. FTIR\−CO spectroscopy confirmed single-site nature of the intermetallic Pd\−In phase reduced at high temperature. Utilization of Pd\−In/Al2O3\ in semihydrogenation of propyne with parahydrogen allowed to produce \≈3400-fold NMR signal enhancement for reaction product propene (polarization=9.3\ \%), demonstrating the large contribution of pairwise hydrogen addition route. Significant signal enhancement as well as the high catalytic activity of the Pd\−In catalyst allowed to acquire\ 1H MR images of flowing hyperpolarized propene gas selectively for protons in CH, CH2\ and CH3\ groups. This observation is unique and can be easily transferred to the development of a useful MRI technique for an in situ investigation of selective semihydrogenation in catalytic reactors.

}, doi = {10.1002/chem.201705644}, url = {https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201705644}, author = {Dudari Burueva and Kirill Kovtunov and Andrey Bukhtiyarov and Danila Barskiy and Igor Prosvirin and Igor Mashkovsky and Galina Baeva and Valerii Bukhtiyarov and Aleksandr Stakheev and Igor Koptyug} }