@article {1627, title = {Zero-field nuclear magnetic resonance spectroscopy of viscous liquids}, journal = {Journal of Magnetic Resonance}, volume = {250}, year = {2015}, month = {01/2015}, pages = {1-6}, doi = {Doi:10.1016/j.jmr.2014.10.012}, author = {Shimizu, Y. and Blanchard, J.W. and Pustelny, S. and Saielli, G. and Bagno, A. and Ledbetter, M.P. and Budker, D. and Pines, A.} } @article {248, title = {Zero-Field NMR Enhanced by Parahydrogen in Reversible Exchange}, journal = {Journal of the American Chemical Society}, volume = {134}, year = {2012}, note = {J Am Chem Soc909GLTimes Cited:2Cited References Count:40}, month = {02/2012}, pages = {3987-3990}, abstract = {

We have recently demonstrated that sensitive and chemically specific NMR spectra can be recorded in the absence of a magnetic field using hydrogenative parahydrogen induced polarization (PHIP)(1-3) and detection with an optical atomic magnetometer. Here, we show that non-hydrogenative para-hydrogen-induced polarization(4-6) (NH-PHIP) can also dramatically enhance the sensitivity of zero-field NMR. We demonstrate the detection of pyridine, at concentrations as low as 6 mM in a sample volume of 250 mu L, with sufficient sensitivity to resolve all identifying spectral features, as supported by numerical simulations. Because the NH-PHIP mechanism is nonreactive, operates in situ, and eliminates the need for a prepolarizing magnet, its combination with optical atomic magnetometry will greatly broaden the analytical capabilities of zero-field and low-field NMR.

}, keywords = {gas}, isbn = {0002-7863}, doi = {Doi 10.1021/Ja2112405}, url = {://WOS:000301550800015}, author = {Theis, T. and Ledbetter, M. P. and Kervern, G. and Blanchard, J. W. and Ganssle, P. J. and Butler, M. C. and Shin, H. D. and Budker, D. and Pines, A.} } @article {266, title = {Zooming In on Microscopic Flow by Remotely Detected MRI}, journal = {Science}, volume = {330}, year = {2010}, note = {Science682BUTimes Cited:12Cited References Count:27}, month = {Nov 19}, pages = {1078-1081}, abstract = {

Magnetic resonance imaging (MRI) can elucidate the interior structure of an optically opaque object in unparalleled detail but is ultimately limited by the need to enclose the object within a detection coil; acquiring the image with increasingly smaller pixels reduces the sensitivity, because each pixel occupies a proportionately smaller fraction of the detector\&$\#$39;s volume. We developed a technique that overcomes this limitation by means of remotely detected MRI. Images of fluids flowing in channel assemblies are encoded into the phase and intensity of the constituent molecules\&$\#$39; nuclear magnetic resonance signals and then decoded by a volume-matched detector after the fluids flow out of the sample. In combination with compressive sampling, we thus obtain microscopic images of flow and velocity distributions similar to 10(6) times faster than is possible with conventional MRI on this hardware. Our results illustrate the facile integration of MRI with microfluidic assays and suggest generalizations to other systems involving microscopic flow.

}, keywords = {biosensor}, isbn = {0036-8075}, doi = {Doi 10.1126/Science.1192313}, url = {://WOS:000284374700036}, author = {Bajaj, V. S. and Paulsen, J. and Harel, E. and Pines, A.} } @article {279, title = {Zero-field remote detection of NMR with a microfabricated atomic magnetometer}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {105}, year = {2008}, note = {P Natl Acad Sci USA266XBTimes Cited:37Cited References Count:26}, month = {Feb 19}, pages = {2286-2290}, abstract = {

We demonstrate remote detection of nuclear magnetic resonance (NMR) with a microchip sensor consisting of a microfluidic channel and a microfabricated vapor cell (the heart of an atomic magnetometer). Detection occurs at zero magnetic field, which allows operation of the magnetometer in the spin-exchange relaxation-free (SERF) regime and increases the proximity of sensor and sample by eliminating the need for a solenoid to create a leading field. We achieve pulsed NMR linewidths of 26 Hz, limited, we believe, by the residence time and flow dispersion in the encoding region. In a fully optimized system, we estimate that for 1 s of integration, 7 x 10(13) protons in a volume of 1 mm(3), prepolarized in a 10-kG field, can be detected with a signal-to-noise ratio of approximate to 3. This level of sensitivity is competitive with that demonstrated by microcoils in 100-kG magnetic fields, without requiring superconducting magnets.

}, keywords = {mri}, isbn = {0027-8424}, doi = {Doi 10.1073/Pnas.0711505105}, url = {://WOS:000253469900009}, author = {Ledbetter, M. P. and Savukov, I. M. and Budker, D. and Shah, V. and Knappe, S. and Kitching, J. and Michalak, D. J. and Xu, S. and Pines, A.} } @article {310, title = {Zero- to low-field MRI with averaging of concomitant gradient fields}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {102}, year = {2005}, note = {P Natl Acad Sci USA898JKTimes Cited:18Cited References Count:22}, month = {Feb 8}, pages = {1840-1842}, abstract = {

Magnetic resonance imaging (MRI) encounters fundamental limits in circumstances in which the static magnetic field is not sufficiently strong to truncate unwanted, so-called concomitant components of the gradient field. This limitation affects the attainable optimal image fidelity and resolution most prominently in low-field imaging. in this article, we introduce the use of pulsed magnetic-field averaging toward relaxing these constraints. It is found that the image of an object can be retrieved by pulsed low fields in the presence of the full spatial variation of the imaging encoding gradient field even in the absence of the typical uniform high-field time-independent contribution. In addition, error-compensation schemes can be introduced through the application of symmetrized pulse sequences. Such schemes substantially mitigate artifacts related to evolution in strong magnetic-field gradients, magnetic fields that vary in direction and orientation, and imperfections of the applied field pulses.

}, keywords = {selection}, isbn = {0027-8424}, doi = {Doi 10.1073/Pnas.0409115102}, url = {://WOS:000227072900009}, author = {Meriles, C. A. and Sakellariou, D. and Trabesinger, A. H. and Demas, V. and Pines, A.} } @article {570, title = {Zero-Field Nmr}, journal = {Accounts of Chemical Research}, volume = {20}, year = {1987}, note = {Accounts Chem ResG2724Times Cited:35Cited References Count:39}, month = {Feb}, pages = {47-53}, isbn = {0001-4842}, doi = {Doi 10.1021/Ar00134a001}, url = {://WOS:A1987G272400001}, author = {Thayer, A. M. and Pines, A.} } @article {572, title = {Zero-Field Nmr of Nematic Liquid-Crystals with Positive and Negative Magnetic-Susceptibility Anisotropies}, journal = {Journal of Physical Chemistry}, volume = {91}, year = {1987}, note = {J Phys Chem-UsG8355Times Cited:4Cited References Count:22}, month = {Apr 9}, pages = {2194-2197}, isbn = {0022-3654}, doi = {Doi 10.1021/J100292a043}, url = {://WOS:A1987G835500043}, author = {Thayer, A. M. and Luzar, M. and Pines, A.} } @article {588, title = {Zero-Field Nmr of Uniaxial and Biaxial Smectic Liquid-Crystals}, journal = {Molecular Physics}, volume = {62}, year = {1987}, note = {Mol PhysL0770Times Cited:2Cited References Count:30}, month = {Oct 20}, pages = {573-583}, isbn = {0026-8976}, doi = {Doi 10.1080/00268978700102411}, url = {://WOS:A1987L077000003}, author = {Luzar, M. and Thayer, A. M. and Pines, A.} } @article {571, title = {Zero-Field Nmr-Study of the Biaxial Smectic-E Phase}, journal = {Liquid Crystals}, volume = {2}, year = {1987}, note = {Liq CrystH5818Times Cited:3Cited References Count:12}, month = {Mar-Apr}, pages = {241-244}, isbn = {0267-8292}, doi = {Doi 10.1080/02678298708086296}, url = {://WOS:A1987H581800012}, author = {Thayer, A. M. and Luzar, M. and Pines, A.} } @article {612, title = {Zero-Field Nmr and Nqr Spectrometer}, journal = {Review of Scientific Instruments}, volume = {57}, year = {1986}, note = {Rev Sci InstrumA7607Times Cited:42Cited References Count:59}, month = {Mar}, pages = {393-403}, isbn = {0034-6748}, doi = {Doi 10.1063/1.1138898}, url = {://WOS:A1986A760700017}, author = {Bielecki, A. and Zax, D. B. and Zilm, K. W. and Pines, A.} } @article {607, title = {Zero-Field Nmr of Small-Amplitude Motions in a Polycrystalline Solid}, journal = {Journal of the American Chemical Society}, volume = {108}, year = {1986}, note = {J Am Chem SocD7238Times Cited:22Cited References Count:21}, month = {Aug 20}, pages = {5113-5116}, isbn = {0002-7863}, doi = {Doi 10.1021/Ja00277a012}, url = {://WOS:A1986D723800012}, author = {Millar, J. M. and Thayer, A. M. and Zax, D. B. and Pines, A.} } @article {597, title = {Zero-Field Nmr of Solid Bis(Mu-Hydrido)Decacarbonyltriosmium}, journal = {Journal of Physical Chemistry}, volume = {90}, year = {1986}, note = {J Phys Chem-UsA5026Times Cited:5Cited References Count:26}, month = {Mar 13}, pages = {1065-1069}, isbn = {0022-3654}, doi = {Doi 10.1021/J100278a021}, url = {://WOS:A1986A502600021}, author = {Zax, D. B. and Bielecki, A. and Kulzick, M. A. and Muetterties, E. L. and Pines, A.} } @article {600, title = {Zero-Field Nuclear-Magnetic-Resonance of a Nematic Liquid-Crystal}, journal = {Journal of Physical Chemistry}, volume = {90}, year = {1986}, note = {J Phys Chem-UsA8609Times Cited:10Cited References Count:32}, month = {Apr 10}, pages = {1577-1581}, isbn = {0022-3654}, doi = {Doi 10.1021/J100399a024}, url = {://WOS:A1986A860900024}, author = {Thayer, A. M. and Millar, J. M. and Luzar, M. and Jarvie, T. P. and Pines, A.} } @article {617, title = {Zero-Field Nmr and Nqr}, journal = {Journal of Chemical Physics}, volume = {83}, year = {1985}, note = {J Chem PhysAtt21Times Cited:105Cited References Count:184}, pages = {4877-4905}, isbn = {0021-9606}, doi = {Doi 10.1063/1.449748}, url = {://WOS:A1985ATT2100005}, author = {Zax, D. B. and Bielecki, A. and Zilm, K. W. and Pines, A. and Weitekamp, D. P.} } @article {621, title = {Zero-Field Nmr and Nqr with Selective Pulses and Indirect Detection}, journal = {Journal of Chemical Physics}, volume = {83}, year = {1985}, note = {J Chem PhysAmg31Times Cited:36Cited References Count:31}, pages = {934-938}, isbn = {0021-9606}, doi = {Doi 10.1063/1.449419}, url = {://WOS:A1985AMG3100004}, author = {Millar, J. M. and Thayer, A. M. and Bielecki, A. and Zax, D. B. and Pines, A.} } @article {640, title = {Zero-Field Nuclear Magnetic-Resonance}, journal = {Physical Review Letters}, volume = {50}, year = {1983}, note = {Phys Rev LettQr621Times Cited:103Cited References Count:21}, pages = {1807-1810}, isbn = {0031-9007}, doi = {Doi 10.1103/Physrevlett.50.1807}, url = {://WOS:A1983QR62100025}, author = {Weitekamp, D. P. and Bielecki, A. and Zax, D. and Zilm, K. and Pines, A.} }