%0 Journal Article %J Journal of the American Chemical Society %D 2013 %T High-Resolution Zero-Field NMR J-Spectroscopy of Aromatic Compounds %A Blanchard, J. W. %A Ledbetter, M. P. %A Theis, T. %A Butler, M. C. %A Budker, D. %A Pines, A. %K density %X

We report the acquisition and interpretation of nuclear magnetic resonance (NMR) J-spectra at zero magnetic field for a series of benzene derivatives, demonstrating the analytical capabilities of zero-field NMR The zeroth-order spectral patterns do not overlap, which allows for straightforward determination of the spin interactions of substituent functional groups. Higher-order effects cause additional line splittings, revealing additional molecular information. We demonstrate resonance linewidths as narrow as 11 mHz, permitting resolution of minute frequency differences and precise determination of long-range J-couplings. The measurement of J-couplings with the high precision offered by zero-field NMR may allow further refinements in the determination of molecular structure and conformation.

%B Journal of the American Chemical Society %V 135 %P 3607-3612 %8 02/2013 %@ 0002-7863 %G English %U ://WOS:000315936700050 %N 9 %M WOS:000315936700050 %! High-Resolution Zero-Field NMR J-Spectroscopy of Aromatic Compounds %R Doi 10.1021/Ja312239v