%0 Journal Article %J Physical Review Letters %D 2007 %T Time-of-flight flow imaging of two-component flow inside a microfluidic chip %A Harel, E. %A Hilty, C. %A Koen, K. %A McDonnell, E. E. %A Pines, A. %K microchannels %X

Here we report on using NMR imaging and spectroscopy in conjunction with time-of-flight tracking to noninvasively tag and monitor nuclear spins as they flow through the channels of a microfluidic chip. Any species with resolvable chemical-shift signatures can be separately monitored in a single experiment, irrespective of the optical properties of the fluids, thereby eliminating the need for foreign tracers. This is demonstrated on a chip with a mixing geometry in which two fluids converge from separate channels, and is generally applicable to any microfluidic device through which fluid flows within the nuclear spin-lattice relaxation time.

%B Physical Review Letters %V 98 %8 Jan 5 %@ 0031-9007 %G English %U ://WOS:000243379700050 %N 1 %M WOS:000243379700050 %! Time-of-flight flow imaging of two-component flow inside a microfluidic chip %R Doi 10.1103/Physrevlett.98.017601