Enhancement of solution NMR and MRI with laser-polarized xenon

TitleEnhancement of solution NMR and MRI with laser-polarized xenon
Publication TypeJournal Article
Year of Publication1996
AuthorsNavon G., Song Y.Q, Room T., Appelt S., Taylor R.E, Pines A
JournalScience
Volume271
Issue5257
Pagination1848-1851
Date PublishedMar 29
ISBN Number0036-8075
Accession NumberWOS:A1996UC77800041
Keywordsresonance
Abstract

Optical pumping with laser light can be used to polarize the nuclear spins of gaseous xenon-129. When hyperpolarized xenon-129 is dissolved in liquids, a time-dependent departure of the proton spin polarization from its thermal equilibrium is observed, The variation of the magnetization is an unexpected manifestation of the nuclear Overhauser effect, a consequence of cross-relaxation between the spins of solution protons and dissolved xenon-129. Time-resolved magnetic resonance images of both nuclei in solution show that the proton magnetization is selectively perturbed in regions containing spin-polarized xenon-129. This effect could find use in nuclear magnetic resonance spectroscopy of surfaces and proteins and in magnetic resonance imaging.

URL<Go to ISI>://WOS:A1996UC77800041
DOI10.1126/Science.271.5257.1848
Short TitleEnhancement of solution NMR and MRI with laser-polarized xenon
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