Gas flow MRI using circulating laser-polarized Xe-129

TitleGas flow MRI using circulating laser-polarized Xe-129
Publication TypeJournal Article
Year of Publication1999
AuthorsBrunner E., Haake M., Kaiser L., Pines A, Reimer J.A
JournalJournal of Magnetic Resonance
Date PublishedMay
ISBN Number1090-7807
Accession NumberWOS:000080303900021

We describe an experimental approach that combines multidimensional NMR experiments with a steadily renewed source of laser-polarized Xe-129. Using a continuous flow system to circulate the gas mixture, gas phase NMR signals of laser-polarized Xe-129 can be observed with an enhancement of three to four orders of magnitude compared to the equilibrium Xe-129 NMR signal. Due to the fact that the gas flow recovers the nonequilibrium Xe-129 nuclear spin polarization in 0.2 to 4 s, signal accumulation on the time scale of seconds is feasible, allowing previously inaccessible phase cycling and signal manipulation. Several possible applications of MRI of laser-polarized Xe-129 under continuous flow conditions are presented here. The spin density images of capillary tubes demonstrate the feasibility of imaging under continuous how. Dynamic displacement profiles, measured by a pulsed gradient spin echo experiment, show entry flow properties of the gas passing through a constriction under laminar flow conditions. Further, dynamic displacement profiles of Xe-129, flowing through polyurethane foams with different densities and pore sizes, are presented. (C) 1999 Academic Press.

URL<Go to ISI>://WOS:000080303900021
Short TitleGas flow MRI using circulating laser-polarized Xe-129
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