Spin coherence transfer in chemical transformations monitored by remote detection NMR

TitleSpin coherence transfer in chemical transformations monitored by remote detection NMR
Publication TypeJournal Article
Year of Publication2007
AuthorsAnwar M.S, Hilty C., Chu C., Bouchard L.S, Pierce K.L, Pines A
JournalAnalytical Chemistry
Volume79
Issue7
Pagination2806-2811
Date PublishedApr 1
ISBN Number0003-2700
Accession NumberWOS:000245304300022
Keywordslab
Abstract

We demonstrate a nuclear magnetic resonance (NMR) experiment using continuous flow in a microfluidic channel for studying the transfer of spin coherence in nonequilibrium chemical processes. We use the principle of remote detection, which involves spatially separated NMR encoding and detection coils. As an example, we provide the map of chemical shift correlations for the amino acid alanine as it transitions from the zwitterionic to the anionic form. The presented method uniquely allows for tracking the migration of encoded spins during the course of any chemical transformation and can provide useful information about reaction mechanisms.

URL<Go to ISI>://WOS:000245304300022
DOI10.1021/Ac062327+
Short TitleSpin coherence transfer in chemical transformations monitored by remote detection NMR
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