Variable-Angle Correlation Spectroscopy in Solid-State Nuclear-Magnetic-Resonance

TitleVariable-Angle Correlation Spectroscopy in Solid-State Nuclear-Magnetic-Resonance
Publication TypeJournal Article
Year of Publication1992
AuthorsFrydman L., Chingas G.C, Lee Y.K, Grandinetti P.J, Eastman M.A, Barrall G.A, Pines A
JournalJournal of Chemical Physics
Date PublishedOct 1
ISBN Number0021-9606
Accession NumberWOS:A1992JR33800022

We describe here a new solid-state nuclear-magnetic-resonance (NMR) experiment for correlating anisotropic and isotropic chemical shifts of inequivalent nuclei in powdered samples. Spectra are obtained by processing signals arising from a spinning sample, acquired in independent experiments as a function of the angle between the axis of macroscopic rotation and the external magnetic field. This is in contrast to previously proposed techniques, which were based on sudden mechanical flippings or multiple-pulse sequences. We show that the time evolution of variable-angle-spinning signals is determined by a distribution relating the isotropic frequencies of the spins with their corresponding chemical shift anisotropies. Fourier transformation of these data therefore affords a two-dimensional NMR spectrum, in which line shapes of isotropic and anisotropic interactions are correlated. Theoretical and experimental considerations involved in the extraction of this spectral information are discussed, and the technique is illustrated by an analysis of C-13 NMR anisotropy in glycine, cysteine, and p-anisic acid.

URL<Go to ISI>://WOS:A1992JR33800022
Short TitleVariable-Angle Correlation Spectroscopy in Solid-State Nuclear-Magnetic-Resonance
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