Publications

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2011
Meldrum T., Bajaj V.S, Wemmer D.E, Pines A.  2011.  Band-selective chemical exchange saturation transfer imaging with hyperpolarized xenon-based molecular sensors. Journal of Magnetic Resonance. 213(1):14-21. PDF
Michalak D.J, Xu S.J, Lowery T.J, Crawford C.W, Ledbetter M., Bouchard L.S, Wemmer D.E, Budker D., Pines A.  2011.  Relaxivity of Gadolinium Complexes Detected by Atomic Magnetometry. Magnetic Resonance in Medicine. 66(2):605-608. PDF
2010
Schilling F., Schroder L., Palaniappan K.K, Zapf S., Wemmer D.E, Pines A.  2010.  MRI Thermometry Based on Encapsulated Hyperpolarized Xenon. Chemphyschem. 11(16):3529-3533. PDF
Meldrum T., Seim K.L, Bajaj V.S, Palaniappan K.K, Wu W., Francis M.B, Wemmer D.E, Pines A.  2010.  A Xenon-Based Molecular Sensor Assembled on an MS2 Viral Capsid Scaffold. Journal of the American Chemical Society. 132(17):5936-+. PDF
Meldrum T., Schroder L., Denger P., Wemmer D.E, Pines A.  2010.  Xenon-based molecular sensors in lipid suspensions. Journal of Magnetic Resonance. 205(2):242-246. PDF
2009
Ledbetter M.P, Crawford C.W, Pines A, Wemmer D.E, Knappe S., Kitching J., Budker D..  2009.  Optical detection of NMR J-spectra at zero magnetic field. Journal of Magnetic Resonance. 199(1):25-29. PDF
2008
Schroeder L., Meldrum T., Smith M., Lowery T.J, Wemmer D.E, Pines A.  2008.  Temperature response of (129)Xe depolarization transfer and its application for ultrasensitive NMR detection. Physical Review Letters. 100(25) PDF
Schroder L., Chavez L., Meldrum T., Smith M., Lowery T.J, Wemmer D.E, Pines A.  2008.  Temperature-controlled molecular depolarization gates in nuclear magnetic resonance. Angewandte Chemie-International Edition. 47(23):4316-4320. PDF
2007
Garcia S., Chavez L., Lowery T.J, Han S.I, Wemmer D.E, Pines A.  2007.  Sensitivity enhancement by exchange mediated magnetization transfer of the xenon biosensor signal. Journal of Magnetic Resonance. 184(1):72-77. PDF
2006
Schroder L., Lowery T.J, Hilty C., Wemmer D.E, Pines A.  2006.  Molecular imaging using a targeted magnetic resonance hyperpolarized biosensor. Science. 314(5798):446-449. PDF
Lowery T.J, Garcia S., Chavez L., Ruiz E.J, Wu T., Brotin T., Dutasta J.P, King D.S, Schultz P.G, Pines A et al..  2006.  Optimization of xenon biosensors for detection of protein interactions. Chembiochem. 7(1):65-73. PDF
Lim K.H, Nguyen T.N, Damo S.M, Mazur T., Ball H.L, Prusiner S.B, Pines A, Wemmer D.E.  2006.  Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L). Solid State Nuclear Magnetic Resonance. 29(1-3):183-190. PDF
Hilty C., Lowery T.J, Wemmer D.E, Pines A.  2006.  Spectrally resolved magnetic resonance imaging of a xenon biosensor. Angewandte Chemie-International Edition. 45(1):70-73. PDF
Mynar J.L, Lowery T.J, Wemmer D.E, Pines A, Frechet J.MJ.  2006.  Xenon biosensor amplification via dendrimer-cage supramolecular constructs. Journal of the American Chemical Society. 128(19):6334-6335. PDF
2005
Lowery T.J, Doucleff M., Ruiz E.J, Rubin S.M, Pines A, Wemmer D.E.  2005.  Distinguishing multiple chemotaxis Y protein conformations with laser-polarized Xe-129 NMR. Protein Science. 14(4):848-855. PDF
Han S.I, Garcia S., Lowery T.J, Ruiz E.J, Seeley J.A, Chavez L., King D.S, Wemmer D.E, Pines A.  2005.  NMR-based biosensing with optimized delivery of polarized Xe-129 to solutions. Analytical Chemistry. 77(13):4008-4012. PDF
2004
Lowery T.J, Rubin S.M, Ruiz E.J, Pines A, Wemmer D.E.  2004.  Design of a conformation-sensitive xenon-binding cavity in the ribose-binding protein. Angewandte Chemie-International Edition. 43(46):6320-6322. PDF
Spence M.M, Ruiz E.J, Rubin S.M, Lowery T.J, Winssinger N., Schultz P.G, Wemmer D.E, Pines A.  2004.  Development of a functionalized xenon biosensor. Journal of the American Chemical Society. 126(46):15287-15294. PDF
2002
Rubin S.M, Lee S.Y, Ruiz E.J, Pines A, Wemmer D.E.  2002.  Detection and characterization of xenon-binding sites in proteins by Xe-129 NMR spectroscopy. Journal of Molecular Biology. 322(2):425-440. PDF
Lim K.H, Nguyen T., Mazur T., Wemmer D.E, Pines A.  2002.  Sensitivity enhancement in multiple-quantum NMR experiments with CPMG detection. Journal of Magnetic Resonance. 157(1):160-162. PDF
2001
Rubin S.M, Spence M.M, Pines A, Wemmer D.E.  2001.  Characterization of the effects of nonspecific xenon-protein interactions on Xe-129 chemical shifts in aqueous solution: Further development of xenon as a biomolecular probe. Journal of Magnetic Resonance. 152(1):79-86. PDF
Rubin S.M, Spence M.M, Dimitrov I.E, Ruiz E.J, Pines A, Wemmer D.E.  2001.  Detection of a conformational change in maltose binding protein by Xe-129 NMR spectroscopy. Journal of the American Chemical Society. 123(35):8616-8617. PDF
Havlin R.H, Laws D.D, Bitter H.ML, Sanders L.K, Sun H.H, Grimley J.S, Wemmer D.E, Pines A, Oldfield E..  2001.  An experimental and theoretical investigation of the chemical shielding tensors of C-13(alpha) of alanine, valine, and leucine residues in solid peptides and in proteins in solution. Journal of the American Chemical Society. 123(42):10362-10369. PDF
Spence M.M, Rubin S.M, Dimitrov I.E, Ruiz E.J, Wemmer D.E, Pines A, Yao S.Q, Tian F., Schultz P.G.  2001.  Functionalized xenon as a biosensor. Proceedings of the National Academy of Sciences of the United States of America. 98(19):10654-10657. PDF
Laws D.D, Bitter H.ML, Liu K., Ball H.L, Kaneko K., Wille H., Cohen F.E, Prusiner S.B, Pines A, Wemmer D.E.  2001.  Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 98(20):11686-11690. PDF

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